The son of Academy Award winner Michael Douglas has been arrested once again — this time in the Big Apple for getting in the middle of a deal to sell an eye-popping pile of crystal meth, law-enforcement sources said yesterday.

The 30-year-old sometime-actor/sometime-DJ was busted on July 28 at the Gansevoort Hotel in the Meatpacking District by a DEA task force, the sources said.

He had been staying at the hotel for some time in a room rented by his father, and when authorities barged in, they found the place a mess and Cameron Douglas “very strung out,” according to the sources.

An informant had told the investigators that Douglas — grandson of Kirk Douglas — was the middleman in a deal to move a half-pound of crystal meth from California to New York to sell.

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